![]() ![]() The aim of this study was to determine the changes in fatty acid profile of milk during weaning process in Damascus goats. Weaning is one of the potential breeding practices that may affects the milk fatty acid profile in goats. During lactation stages, there are notable changes in the fatty acid profile of goat milk. ![]() Weaning in goat breeding is applied with varying periods and practices. Saanen goat's milk proteins, on the other hand, cross-reacted with two major milk allergens, α-S1-CN and β-LG, whereas Toggenburg goat's milk proteins only react with one of the major milk allergens, κ-CN. Jamnapari's milk proteins were found to cross-react with four major milk allergens: α-S1-CN, β-CN, κ-CN, and β-LG. The analysis of IgE-reactive proteins revealed that the protein spots identified with high confidence were proteins homologous to common cow's milk allergens such as α-S1-casein (αS1-CN), β-casein (β-CN), κ-casein (κ-CN), and beta-lactoglobulin (β-LG). IgE-immunoblotting and mass spectrometry were used to compare and identify proteins that cross-reacted with serum IgE from CMPA patients (n = 10). Proteomics was used to compare protein extracts of skim milk from Saanen, Jamnapari, and Toggenburg. ![]() This study aimed to profile and compare milk proteins from different goat breeds that have cross-reactivity to cow's milk allergens. However, there is growing evidence that their proteins have cross-reactivities with cow's milk allergens. Goat’s milk thought to be a good substitute for cow's milk protein allergic (CMPA) individuals. ![]()
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